Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Tardive dyskinesiaUpdated: 2021-11-19OverviewTardive dyskinesia is typically caused by long-term use of dopamine-blocking drugs, most commonly antipsychotic (neuroleptic) drugs or an anti-nausea medication called metoclopramide.SymptomsTardive dyskinesia includes a wide range of involuntary movements. Most commonly these movements involve the mouth, tongue and face, but may also affect the trunk or limbs.TreatmentsStopping the offending antipsychotic or anti-nausea drugs may stop the movements. Medications to relieve the symptoms, botulinum toxin injections or deep brain stimulation may be recommended. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use