Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Spider biteUpdated: 2017-06-13OverviewA spider bite is an injury caused by venom from a spider's bite. In the U.S., only black widows and brown recluse spider bites are a threat. These spiders generally live in undisturbed areas, such as attics or sheds, and don't bite unless threatened.TreatmentsTreatment usually includes cleaning the bite, applying ice, and watching for infection. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use