Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Piriformis syndromeUpdated: 2017-06-13OverviewPiriformis syndrome an uncommon disorder of a narrow muscle located in the buttocks. SymptomsSymptoms include pain, tingling, or numbness in the buttocks and down the leg, which may worsen after sitting for a long time, climbing stairs, walking, or running. TreatmentsTreatments include stretching exercises, massage, anti-inflammatory drugs, or surgery. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use