Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Necrotizing fasciitisUpdated: 2019-12-10OverviewNecrotizing fasciitis is a serious bacterial infection. It spreads quickly and destroys tissue under the skin. The infection is contracted through a skin break. Most people who get the infection have a weakened immune system.SymptomsSigns and symptoms include blisters, pain, fever, fatigue and vomiting.TreatmentsAntibiotics and surgery can help stop infection. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use