Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs ElephantiasisUpdated: 2020-04-07OverviewElephantiasis is a condition in which lymphatic blockage causes massive limb swelling. The blockage causes lymph fluid to build up in the affected area. Skin hardens to become like elephant skin. Causes include a parasitic disease or an infection.TreatmentsElevating and pressure wrapping the affected area can help. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use