Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Diastolic heart failureUpdated: 2017-06-13OverviewDiastolic heart failure is a condition in which the heart's left ventricle can't relax or fill fully. The left ventricle is the heart's main pumping chamber.SymptomsSymptoms might include shortness of breath, leg swelling, and fatigue.TreatmentsTreatments include medications. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use