Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Carpal tunnel syndromeUpdated: 2017-06-13OverviewCarpal tunnel syndrome is a condition that includes numbness, tingling, and weakness in the hand and arm, caused by a pinched nerve in the wrist. Wrist anatomy, underlying health conditions, and patterns of hand use can contribute to the syndrome.TreatmentsTreatment may include rest, ice, wrist splints, cortisone injections, and surgery. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use