Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs ParotitisUpdated: 2017-06-13OverviewParotitis is swelling of 1 or both of the largest saliva-producing glands inside the cheeks (parotid glands). The glands may feel tender and may contain pus.The most common cause is mumps. Other causes include the flu, staph infection, and diabetes.TreatmentsWhen the underlying condition is treated, it clears up. Treatment may include antibiotics. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use