Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs PapuleUpdated: 2020-09-03Self-careOver-the-counter medications include products containing benzoyl peroxide as the active ingredient. Washing skin with a gentle cleanser and using oil-free moisturizer may help.When to seek immediate medical careSee a doctor immediately if: Fever Weight loss When to make a doctor's appointmentMake an appointment to see a doctor if: Home remedies don't clear up skin Spread over the body Not healing Color darkens © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use