Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Myofascial pain syndromeUpdated: 2019-10-10OverviewMyofascial pain syndrome is a disorder in which pressure on sensitive points in the muscles causes pain in seemingly unrelated body parts. The syndrome often happens after repeated injury or muscle overuse. SymptomsSymptoms include persistent pain or a tender muscle knot. TreatmentsTreatments include physical therapy, medications, and relaxation techniques. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use