Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Muscular dystrophyUpdated: 2020-01-31OverviewIn muscular dystrophies, abnormal genes (mutations) lead to muscle degeneration. Most forms begin in childhood.SymptomsDamaged muscles become progressively weaker. Most people who have the condition eventually need a wheelchair. Other symptoms include trouble breathing or swallowing.TreatmentsMedications, therapy, breathing aids or surgery may help maintain function, but life span is often shortened. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use