Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Muscle painUpdated: 2018-05-24Self-careSelf-care options include rest, ice, compression, and elevation (RICE). Over-the-counter acetaminophen (Tylenol) and ibuprofen (Advil, Motrin IB, others) can help, too. When to seek immediate medical careSee a doctor immediately if: Trouble breathing or dizziness Extreme muscle weakness High fever and stiff neck When to make a doctor's appointmentMake an appointment to see a doctor if: Accompanied by a tick bite or rash Worsens with exercise and resolves with rest, especially in the calves Redness and swelling Follows a change in medication or dosage © 1998-2019 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use