Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs CallusUpdated: 2020-04-21Self-careSoak the callused area frequently in warm, soapy water, and then use a pumice stone to rub off hardened skin. Follow up with moisturizer. When to seek immediate medical careSee a doctor immediately if: Diabetes Poor blood flow When to make a doctor's appointmentMake an appointment to see a doctor if: Painful callus Inflammation Painful break in skin © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use