Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Bone diseaseUpdated: 2017-06-13OverviewBone disease is any type of condition or disease that affects the bones. Bone loss can occur with aging (osteoporosis). Poor nutrition or too little calcium and vitamin D can weaken bones. Like the soft tissues, bones can become cancerous or infected.SymptomsSymptoms vary depending on the condition.TreatmentsTreatments also vary depending on the condition. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use