Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs AtheromaUpdated: 2017-06-13OverviewAn atheroma is a mass of fats, cholesterol, and other substances (plaque) in and on artery walls. Atheromas restrict blood flow. They can also burst, triggering a blood clot.TreatmentsA healthy diet and exercise can help reduce plaque. Treatments include medications, procedures to flatten plaque and hold arteries open, and surgery. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use