Menu Healthy Lifestyle Diseases & Conditions First Aid Symptoms Tests & Procedures Videos Definitions FAQs Adrenal insufficiencyUpdated: 2017-06-13OverviewIn Addison's disease (adrenal insufficiency), the small glands above the kidneys (adrenal glands) don't make enough of certain hormones.SymptomsSymptoms include weakness, weight loss, darkening of the skin, and low blood pressure.TreatmentsTreatment includes hormone replacement therapy. © 1998-2022 Mayo Foundation for Medical Education and Research(MFMER). All rights reserved. Terms of Use