DefinitionApolipoprotein B100 (apo B100) is a protein that plays a role in moving cholesterol around your body. It is a form of low density lipoprotein (LDL).This article discusses the test used to measure the level of apoB100 in the blood.
Alternative NamesApoB100; Apoprotein B100
How the test is performedA blood sample is needed. For information on how this is done, see: Venipuncture
How to prepare for the testYour health care provider may tell you not to eat or drink anything for 4 - 6 hours before the test.
How the test will feelWhen the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the test is performedMost often, this test is done to help determine the cause or specific type of hyperlipidemia.
Normal ValuesThe normal range is 50 - 150 mg/dL.Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.
What abnormal results meanAn abnormal result may mean you have high lipid levels (hyperlipidemia).Other disorders that may be associated with high apoB100 levels include angina pectoris and heart attack.See also: Familial combined hyperlipidemia
What the risks areExcessive bleeding
Fainting or feeling light-headed
Hematoma (blood accumulating under the skin)
Infection (a slight risk any time the skin is broken)
Multiple punctures to locate veins
Special considerationsApolipoprotein measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a lipid panel is unknown.
ReferencesGenest J, Libby P. Lipoprotein disorders and cardiovascular disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, PA:Saunders Elsevier; 2011:chap 47. Semenkovich, CF. Disorders of lipid metabolism. In: GoldmanL, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 213.